AB1607 TREATMENT OUTCOME OF RHEUMATOID ARTHRITIS IN RURAL AND URBAN POPULATION; A COMPARATIVE STUDY FROM SOUTH INDIA

Background Advances in rheumatology have made the once-disfiguring rheumatoid arthritis (RA) a controllable disease. However, differences health care delivery exist across rural and urban populations South India. Hence disease characteristics may be different two groups of patients. [1,2] Herein, we compare RA based state Kerala Objectives The primary objective was to centres Methods A retrospective study patients attending clinics our Institute conducted. Consecutive 100 who attended from April October 2022 satisfied ACR/EULAR 2010 criteria were selected for each group. Baseline Demographics collected, activity measured using CDAI score. Extraarticular manifestations comorbidities associated with also considered. Treatment response assessed at end 6 months. Results mean age 51 years(± 12SD) 55 years(±12SD) groups, respectively. Disease baseline six months shown Figure 1. 28% required triple DMARDs control against 14% group (p-value 0.02). Remission attained 47% population 30% 0.05). Non-alcoholic Fatty liver more prevalent (9%) than (2%)(p-value DMARD-induced elevation enzymes occurred 15% compared 5% group(Pvalue-0.03). Even though prevalence uncontrolled T2DM osteoarthritis population, difference between not statistically significant. Similarly, use biologicals (8%) (4%) without any statistical significance. Conclusion We observed that identical both groups. At months, CRP significantly higher suggesting optimal DMARD treatment better Triple This shows despite advances rheumatology, there are still unmet needs regarding awareness access adequate society. References [1] Lekpa, F.K., Ndongo, S., Tiendrebeogo, J. et al. Rheumatoid Senegal: comparison areas, an tertiary center Senegal. Clin Rheumatol 31, 1617–1620 (2012). [2] Kumar P, Alok R, Das SK, Srivastava Agarwal GG. Distribution rheumatological diseases areas: An adapted COPCORD Stage I Phase III survey Lucknow district north Int J Rheum Dis. 2018 Nov;21(11):1894-1899. Acknowledgements: NIL. Disclosure Interests None Declared.